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Featured Citations
Tracking transcription-translation coupling in real time. Qureshi NS, Duss O. Nature. 2025 Jan 9;637(8045):487–495.
Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture. Pourmal S, Truong ME et al. Nature. 2025 Jan 9;637(8045):446–452.
Dual-action kinase inhibitors influence p38α MAP kinase dephosphorylation. Stadnicki EJ, Ludewig H et al. Proc Natl Acad Sci USA. 2025 Jan 7;122(1):e2415150122.
Chemical bond overlap descriptors from multiconfiguration wavefunctions. Santos-Jr CV, Kraka E, Moura RT Jr. J Comput Chem. 2025 Jan 5;46(1):e27534.
Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease. Fowler SL, Behr TS et al. Nat Neurosci. 2025 Jan;28(1):40-48.
More citations...News
December 25, 2024
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December 12, 2024
The ChimeraX 1.9 production release is available! See the change log for what's new.
October 14, 2024
Planned downtime: The ChimeraX website, Toolshed, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable starting Monday, Oct 14 10 AM PDT, continuing throughout the week and potentially the weekend (Oct 14-20).
Previous news...Upcoming Events
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.
ChimeraX is developed with support from National Institutes of Health R01-GM129325, Chan Zuckerberg Initiative grant EOSS4-0000000439, and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.
Feature Highlight
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 |
A cryoelectron microscopy map of the 26S proteasome
(EMD-4321) is shown at the author-recommended contour level
in two different lighting modes: “simple” on the left
and “soft” on the right.
Soft lighting includes ambient lighting and shadowing (occlusion)
and can be turned on with the command
lighting soft
or by clicking the
Graphics
icon
.
For setup of the righthand image, see the command file ambient.cxc.
More features...Example Image
The photosynthetic reaction center from a
purple sulfur bacterium is shown as a cartoon with “tube” helices
and membrane boundaries from the OPM database (Orientations of Proteins in Membranes,
entry 1eys).
Blue and red balls represent the cytoplasmic and periplasmic sides
of the bacterial inner membrane, respectively.
The title and other text labels were added with the
2dlabels
command and repositioned interactively with the move label
mouse mode
.
ChimeraX session file: prc.cxs
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