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Recent Citations

Structure and mechanism of the SGLT family of glucose transporters. Han L, Qu Q et al. Nature. 2022 Jan 13;601(7892):274–279.

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex. Patil DN, Singh S et al. Science. 2022 Jan 7;375(6576):86-91.

Structure and plasticity of indoleamine 2,3-dioxygenase 1 (IDO1). Röhrig UF, Michielin O, Zoete V. J Med Chem. 2021 Dec 23;64(24):17690-17705.

Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2. Fukudome A, Singh J et al. Proc Natl Acad Sci USA. 2021 Dec 21;118(51):e2115899118.

The conformational cycle of prestin underlies outer-hair cell electromotility. Bavi N, Clark MD et al. Nature. 2021 Dec 16;600(7889):553–558.

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News

December 17, 2021

Chimera production release 1.16 is now available. This will be the last release to support Windows 7. See the release notes for what's new.

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

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Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

Volume Data

Volume Data

Chimera's Volume Viewer displays three-dimensional electron and light microscope data, X-ray density maps, electrostatic potential and other volumetric data. Contour surfaces, meshes and volumetric display styles are provided and thresholds can be changed interactively. Maps can be colored, sliced, segmented, and modifications can be saved. Markers can be placed and structures can be traced. The accompanying image shows a density map of Kelp fly virus from electron microscopy colored radially and with an octant cut out.

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Gallery Sample

Molecular Bracelet

Eukaryotic initiation factor (eIF) complex (from Protein Data Bank entry 1rf8) in which eIF4E, shown with blue ribbons, is completely encircled by eIF4G, shown with yellow ribbons and red molecular surface (image creation details). (More samples...)


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